Glycoproteins and blood group activity. Oligosaccharides of A+ hog submaxillary glycoproteins.
نویسندگان
چکیده
منابع مشابه
Effect of sialidase on blood group specificity of hog submaxillary glycoproteins.
Hogs can be divided into three phenotypes A, H and In, depending on the ability of extracts of their submaxillary glands to inhibit the agglutination of human A cells with human anti-A, and human O cells with eel-anti-H serum. Evidence is here provided that the inactive glycoprotein, In, represents H active glycoprotein containing additional N-glycolyl neuraminic acid, which stereospecifically ...
متن کاملStructure determination of oligosaccharides isolated from A+, H+ and A-H- hog-submaxillary-gland mucin glycoproteins, by 360-MHz 1H-NMR spectroscopy, permethylation analysis and mass spectrometry.
Alkaline borohydride reductive cleavage (beta-elimination) of hog submaxillary glycoproteins from three immunologically determined phenotypes, viz. A+, H+ and A-H-, resulted in the release of a series of neutral and acidic oligosaccharide-alditols. 360-MHz 1H-NMR spectroscopy in combination with methylation analysis and mass spectrometry were used for reinvestigation of the structures of these ...
متن کاملStructural characterization of neutral oligosaccharides with blood-group A and H activity isolated from bovine submaxillary mucin.
In this study we investigated the structures of 11 neutral oligosaccharides released from bovine submaxillary mucin by alkaline borohydride treatment and isolated by h.p.l.c. One hexa-, one penta-, three tetra-, four tri- and two di-saccharides containing core types 1, 2, 3 or 4 were obtained. We report their structures, determined by a combination of one- and two-dimensional 1H n.m.r. spectros...
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In spite of the abundance of glycoproteins in biological processes, relatively little three-dimensional structural data is available for glycan structures. Here, we study the structure and flexibility of the vast majority of mammalian oligosaccharides appearing in N- and O-glycosylated proteins using a bottom up approach. We report the conformational free-energy landscapes of all relevant glyco...
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We labeled surface glycoproteins of norby polyacrylamide slab gel electrophoresis. mal human blood platelets, granulocytes, All major types of human leukocytes monocytes, T and B lymphocytes, and null showed different and characteristic surcells by the galactose oxidase-NaB3H4 face glycoprotein patterns. These patterns and periodate-NaB3H4 labeling techevidently also include common comniques. T...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1979
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(17)37723-2